Down-home Southern cooking made with love, fresh ingredients, and recipes that have been passed down through generations on Main Street.
Est.
Greenwood, SC
Southern Soul on Main isn't just a restaurant — it's where the flavors of the South come alive. Located right on Greenwood's Main Street, we bring you the kind of cooking that makes you feel like you're sitting at the family table.
Every dish is crafted from scratch using locally sourced ingredients and time-honored recipes. From our signature fried chicken to our slow-smoked barbecue, each plate tells a story of heritage, hospitality, and heartfelt cooking.
Locally sourced ingredients every day
Recipes passed through generations
Step inside Southern Soul on Main — where every corner feels like home and every meal is a celebration.
We're right on Main Street in the heart of Greenwood. Pull up a chair, take a deep breath, and let us take care of the rest.
312 Main St, Greenwood, SC 29646-2758
Monday – Thursday: 11am – 9pm
Friday – Saturday: 11am – 10pm
Sunday: 12pm – 8pm
Whether it's a quick lunch or a family dinner, Southern Soul on Main is ready to serve you something special.
